ISAAC Resources - ISAAC Phase Four
ISAAC Phase Four is the development and expansion of the scope of the ISAAC website and the creation of this resources section for ISAAC collaborators especially those in low and middle income countries. Management guidelines and other resources will be listed here. Management guidelines which appear on this website are free of pharmaceutical industry sponsorship.
Do you know of any such guidelines?
More guidelines for children which were not sponsored by the pharmaceutical industry will be added to the ISAAC website as they become available. If you know of any such guidelines please contact Eamon Ellwood.
General Resources
The Global Asthma Network
The ISAAC Programme formally finished in December 2012. The Global Asthma Network was founded in 2012 and is continuing the work of ISAAC in the asthma field. The Global Asthma Network was established in 2012 to improve asthma care globally, with a focus on low- and middle-income countries, through enhanced surveillance, research collaboration, capacity building and access to quality-assured essential medicines. View the Network
The Network is a collaboration between individuals from the International Study of Asthma and Allergies in Childhood (ISAAC) and the International Union Against Tuberculosis and Lung Disease (The Union). The Global Asthma Network is built on the work achieved by the ISAAC programme 1991-2012. It operates on the same principle of collaborative and systematic application of standardised methodologies. The global asthma surveillance work pioneered by ISAAC merged with the activities that The Union has pursued over the years in field evaluation and research into the management of asthma; access to quality-assured, affordable essential asthma medicines; and operational research and capacity-building.
since its inception the GlobalAsthma Network has:
- continued asthma research including updating the ISAAC Environmental questionnaire and conducted another round of surveilance; View GAN publications
- publishing 5 Global Asthma Reports (latest below); View reports
- maintained and built on the ISAAC network - View GAN Centres
Vist the Global Asthma Network website for the latest in asthma research. View GAN website
Global Asthma Report 2025: Patient Stories
The Global Asthma Network is delighted to introduce the Global Asthma Report (GAR): Patient Stories - an exciting special edition format for the GAR that gives people with asthma from around the world a platform to tell their stories. This is the fifth in our series of GARs published in 2011, 2014, 2018 and 2022
Global Asthma Report 2022
The Global Asthma Report 2022 is the fourth in a series published in 2011, 2014 and 2018. It is a 102-page cutting edge State-of-the-Art report, with contributions from 97 experts from, 31 countries. The focus is on reducing the burden of asthma and improving asthma management. The section on the six WHO regions, includes insightful accounts.
The Global Asthma Report 2022 was officially launched at the International Union Against Tuberculosis and Lung Disease World Conference on Lung Health 2022 on 10 November 2022
The report can be accessed at www.globalasthmareport.org
European Respiratory Monograph
The European Respiratory Society (ERS) has recently published the Paediatric Asthma issue of its quarterly book series, the European Respiratory Monograph (ERM). The issue is Guest Edited by leaders in the field Professor Kai-Håkon Carlsen and Professor Jorrit Gerritsen, who have brought together distinguished pulmonologists to provide a comprehensive review of paediatric asthma. All aspects of paediatric asthma are covered, from birth to the start of adulthood, and the issue includes chapters on: asthma phenotypes; physical exercise; food allergy and anaphylaxis; genetics and epigenetics; pollution; asthma treatment; and psychological factors. This issue of the ERM book series should prove a useful resource in daily clinical practice, and it is hoped that young pulmonologists in particular will find this a source of inspiration in their future work.
ERS members can freely access the Paediatric Asthma issue online at http://erspublications.com/content/paediatric-asthma. To purchase a print copy of the issue or to find out more about the ERM, contact monograph@ersj.org.uk
Lectures by ISAAC Steering Committee members
ISAAC 20 Year Anniversary Symposium - Auckland 2011
The ISAAC 20 Year Anniversary Symposium was held in the Fisher and Paykel Auditorium, Owen G Glenn Building, The University of Auckland on Thursday 27th of January 2011
News article
The Symposium was hosted by The University of Auckland and Massey University, and officially opened by Hon. Tariana Turia, Associate Minister of Health. Lectures of ISAAC findings in various aspects of allergic diseases were given by members of the ISAAC Steering Committee. Pdf files of these presentations are now available for download here.
Auckland Medical Research Foundation Public Lecture:
Asthma and allergies: Where in the world are we now?
Professor Innes Asher shared the highlights of the ISAAC work and recent Symposium at this public lecture hosted by the Auckland Medical Research Foundation. In this lecture Professor Asher highlighted the changes
in thinking about asthma and allergies over the last 20 years.
download slides | view presentation
Auckland Starship Childrens Hospital Paediatric Update
Auckland Starship Childrens Hospital Paediatric Update October 2010. View Professor Innes Asher�s presentation on �Asthma and allergies - where in the world have we got to? ISAAC from 1991 to 2010�.
View Presentation
ATS Conference New Orleans 2010
American Thoracic Society International Conference in New Orleans May 2010. View Professor Innes Asher�s presentation on �Asthma Disparities: a Global View�.
download notes
ISAAC Symposium - Mérida 2009
The ISAAC symposium was held in the Manuel Cepeda Peraza Auditorium in the Central Building of the Autonomous University of Yucatan (Universidad Autónoma de Yucatán) on Saturday 28th of November 2009
News article from University of Yucatan
The Symposium was hosted by Professor Manuel Baeza Bacab, the ISAAC National Co-ordinator for Mexico, and officially opened by the Director of the university, Alfredo Dájer Abimerhi, MVZ M. Phil. Lectures of ISAAC findings in various aspects of allergic diseases were given by 6 members of the ISAAC Steering Committee. Pdf files of these presentations can be downloaded below.
Allergy, Genetics and Environment.
Alergia, Genética y Ambiente.
Professor Neil Pearce
Download
World-Wide Map of the Prevalence of Rinoconjunctivitis in Children.
Mapa Mundial de la prevalencia de Rinoconjunctivitis en Niños.
Professor Luis García-Marcos
Download
Asthma in Latin America.
Asma en América Latina.
Professor Javier Mallol
Coming soon
Global Epidemiology of Allergic Diseases.
Epidemiología Global de las Enfermedades Alérgicas.
Professor Innes Asher
Download
Atopic Eczema.
Eccema Atópico.
Professor Hywel Williams
Download
Hygiene: Relationship between Allergic Diseases and
Infection.
Higiene: Relación entre Enfermedades Alérgicas e Infección.
Professor David Strachan
Download
Asthma - Indigenous Resources
Maori Asthma Review (1991)
Maori Asthma Review Update (2000)
Asthma management interventions
Asthma management intervention and evaluation in a developing country
Sunia Foliaki, Toakase Fakakovikaetau, Wendyl D'Souza, Sione Latu, Viliami Tutone, Soo Cheng, Neil Pearce. Reduction in asthma morbidity following a community-based asthma self-management programme in Tonga. International Journal of Tuberculosis and Lung Disease 2008; 13(1):142�147. Contact: Dr Sunia Foliaki S.Foliaki@massey.ac.nz
Eczema Resources
DermNet NZ
DermNet NZ was established by the New Zealand Dermatological Society, the national association of New Zealand registered dermatologists, to provide information about skin diseases, conditions and treatment for patients and their health professionals. http://dermnetnz.org/
Skin Examination Manual
This Manual produced by Prof. Hywel C. Williams at the Centre of Evidence Based Dermatology in Nottingham, UK, is designed to aid in examining study participants physically for flexural eczema. It consists of an online set of training images and a quality control test for fieldworkers to ensure standardisation of study methods. It can be found at: https://www.nottingham.ac.uk/research/groups/cebd/resources/uk-diagnostic-criteria-for-atopic-dermatitis.aspx.
Eczema resources at NHS Evidence
Each year NHS Evidence � skin disorders undertakes an annual evidence update on atopic eczema. The update includes new guidelines and new systematic reviews published in the preceding year, and involves a detailed commentary of the clinical implications of the new evidence by Hywel Williams and other colleagues
Overview of systematic reviews of eczema prevention
Michelle Foisy, Robert J. Boyle, Joanne R. Chalmers, Eric L. Simpson, Hywel C. Williams. The prevention of eczema in infants and children: an overview of Cochrane and non-Cochrane reviews Evidence-Based Child Health: A Cochrane Review Journal Volume 6, Issue 5, pages 1322�1339, September 2011
GREAT database
The Global Resource for Eczema Trials (GREAT) is an international collection of all randomized controlled trials published since the year 2000 that is free for anyone to use.
Patient Oriented Eczema Measure (POEM)
A quick instrument to measure those aspects about eczema severity that matter to patients
Eczema clinic record sheet
� for use in a clinical setting to be filled in by parents before consultation
Harmonising Outcome Measures for Eczema
The Harmonising Outcome Measures for Eczema project is all about trying to reduce the current long list of outcome measures used in eczema clinical trials to 3 or 4 measures that all future trials can use. Many of the previous scoring systems for eczema have never been validated properly, and it is almost impossible to make any sense of the trial evidence base since different studies have used different outcomes. The HOME project hopes to come up with a list of core outcome measures that should be measured in all future eczema trials.
HOME Website (http://www.homeforeczema.org)
Other Useful Links
Scientific American April 2011: why-are-asthma-rates-soaring
Asthma Drug Facility (ADF)
The Asthma Drug Facility provides affordable access for low and middle income countries to quality assured essential asthma drugs. It was established by the International Union Against Tuberculosis and Lung Disease (IUATLD) with the support of partners such as the World Health Organization (WHO). In addition to the lower the cost of essential asthma medicines, ADF offers technical assistance and support and a strategy for management of asthma to medical practitioners in low and middle income countries.
ADF Website (http://www.globaladf.org)
Asthma Foundation of New Zealand
The Asthma Foundation of New Zealand is New Zealand�s not-for-profit sector authority on asthma and other respiratory illnesses
The International Study of Wheezing in Infants (Estudio Internacional de Sibilancias en Lactantes [EISL]) English | Spanish
EISL is an international cross-sectional multi-centre study designed to assess the prevalence, severity and other factors related to infant wheezing during the first year of life in Latin America and the Iberian Peninsula. EISL has Spanish and English language web sites.
Nomenclature of Allergic Disease, World Allergy Organisation (WAO)
The report of the WAO Nomenclature Review Committee, updating the EAACI Nomenclature Position Statement published in 2001, was published in the Journal of Allergy and Clinical Immunology in May 2004 (J Allergy Clin Immunol 2004; 113: 832-6). The aim of the report is to present a globally acceptable nomenclature for allergic diseases, with the ultimate goal of improving communication in the field of allergy. The nomenclature can be used independently of target organ or patient age group, and is based on the mechanisms which initiate and mediate allergic reactions. As knowledge about basic causes and mechanisms continues to improve, the nomenclature will be reviewed and updated on a triennial basis. This web page includes a summary of the terminology in 23 languages.
Data Analysis
Below are links to some useful articles on ISAAC Data entry and Data analysis written by members of the ISAAC International Data Centre. These articles were published in the bi-annual ISAAC newsletter.
Analysis of ISAAC Phase Three Study Survey Data from One Centre. ISAAC Newsletter December 2001
Analysis of ISAAC Phase Three Study Survey Data from One Centre (Part 2). ISAAC Newsletter April 2002
Phase Three Data Entry. ISAAC Newsletter April 2002
ISAAC Phase Three Data Entry - Part2: Epi-Info - Important features you may need to know ISAAC Newsletter July 2002
Funding of ISAAC Phase Four
ISAAC Phase Four has received funding from the Hawke�s Bay Medical Research Foundation and The University of Auckland, New Zealand