Local Publications

The following publications used ISAAC data from the Marseille centre:

  • Ramadour M, Burel C, Lanteaume A, Vervloet D, Charpin D, Dutau H, Brisse F. Prevalence of asthma and rhinitis in relation to long-term exposure to gaseous air pollutants. Allergy 2000; 55(12): 1163–1169.

Marseille Centre

Phase OnePhase TwoPhase Three
Centre:Marseille, France ( Western Europe )
Principal Investigator:Professor Denis Charpin
Age Groups:13-14Timeframe:
Sampling Frame:Schools were randomly chosen from 8 towns in the Fos L'Etang-de-Berre area.

Personnel

Professor Denis Charpin

Professor Denis Charpin

Service de Pneumologie-Allergologie
Hôpital Nord


France

Roles:

  • National Coordinator for France
  • Phase One Principal Investigator for Marseille

ISAAC phase 1 in the Marseille center has actually taken place in an industrial setting close to Marseille, called the « Fos l’Etang-de-Berre » area. This is a major industrial complex with petrochemicals facilities. The survey used a standardized ISAAC questionnaire,skin tests to common aero-allergens and, in atopic children, collection of a sample of mattress dust to measure mite-allergen contant. At that time, only gaseous air pollutants were considered. 2445 schoolchildren 13 and 14 years old were included in the study. The prevalence of asthma and asthmatics symptoms were related to mean ozone concentrations, whereas there was no consistent association with mean SO2 and NO2 mean levels (M. Ramadour el al. Prevalence of asthma and rhinitis in relation to long-term exposure to gaseous air pollutants. Allergy 2000 ; 55 : 1163-1169. In a concurrent study there was no significant association between gaseous air pollutant levels and the atopic score based on skin prick-tests results (D. Charpin et al. Gaseous air pollution and atopy. Clin Exp Allergy 1999 ; 29 : 1474-1480.