Local Publications
The following publications used ISAAC data from the Madrid centre:
- García-Marcos L, Ruiz TR, García-Hernández G, Morales Suárez-Varela MM, Valverde-Molina J, Sánchez-Solis M. Asthma and rhinoconjunctivitis comorbidity: United airway disease or inherited target organs? Pediatr Allergy Immunol 2010; 21 (1): e142-e148. E pub 7 Apr 2009.
- Morales Suárez-Varela MM, García-Marcos AL, González DC, et al. Prevalence of atopic eczema and nutritional factors in 6-7 year old children.[article in spanish]. Aten Primaria 2007; 39(7):355-360.
- Arnedo-Pena A, García-Marcos L, Fernández-Espinar JF, Bercedo-Sanz A, Aguinaga-Ontoso I, González-Díaz C, Carvajal-Urueña I, Busquet-Monge R, Suárez-Varela MM, de Andoín NG, Batlles-Garrido J, Blanco-Quirós A, López-Silvarrey Varela A, García-Hernández G. Sunny hours and variations in the prevalence of asthma in schoolchildren according to the International Study of Asthma and Allergies (ISAAC) Phase III in Spain. Int J Biometeorol 2011; 55(3): 423-434
Madrid Centre
Phase OneView Centre Details | Phase TwoView Centre Details | Phase Three | |||
Centre: | Madrid, Spain ( Western Europe ) | ||||
Principal Investigator: | Dr Gloria García-Hernández | ||||
Age Groups: | 13-14, 6-7 | Timeframe: | May 2002 to November 2002 | ||
Sampling Frame: | All schools in 11th Health District of Madrid, Spain, The same sampling frame as Phase One. |
Personnel
Dr Gloria García-Hernández
Division of Paediatric Pulmonology and Allergy
Hospital Universitario 12 de Octubre
Avenida de Cordoba S/N
Spain
Roles:
- Phase One Principal Investigator for Madrid
- Phase Two Principal Investigator for Madrid
- Phase Three Principal Investigator for Madrid
Carmen Luna-Paredes
Hospital Doce de Octubre
Madrid
Spain
Roles:
- Phase Three collaborator for Madrid
Antonio Martínez
Hospital Doce de Octubre
Madrid
Spain
Roles:
- Phase Three collaborator for Madrid
ISAAC In Madrid
Although the first meeting for spanish researchers interested in ISAAC study was hosted in Madrid in 1993, it was not until 1996 that our centre entered the first Phase of this project, a unique opportunity to obtain epidemiological data on asthma and allergies in our paediatric population and the possibility to compare it to that of other regions and countries. Eager encouragement to participate came from our country coordinator, Profesor Luis García-Marcos, and we felt we could not let pass this ongoing chance.
Phase One
Madrid was included in Phase One of ISAAC in 1996. Our centre included children of the two age groups. All schools within our sanitary area were invited to participate in the study. Since external funding was not available at the time, we had to count on good will from the members of the team, Dr. García Hernández, Dr Martínez Gimeno and Dr. Carmen Luna who dedicated their time and effort to ensure the study met deadlines. We were very proud of the results that came out of this first study and that helped us know more about the prevalence of asthma and allergies in our setting. An interesting finding was that our prevalence of asthma was higher than that of coastal centres.
Phase Two
Madrid was one of the four centres to participate in Phase Two of the study in Spain. We chose the 100 wheezers plus 100 non-wheezers option in the bronchial challenge test. Field workers had to be trained in atopic dermatitis evaluation, allergy tests (prick tests), pulmonary function tests and data collection following instructions from ISAAC. Funds obtained from the Spanish government, thanks to efforts by our country coordinator, allowed us to encourage our young collaborators in pursuing best results for the study. We found it was a very time consuming effort but the outcomes paid out for it.
Phase Three
This time, Madrid obtained individual funds to pursue this Phase of a study that was already well known all around the world. We surveyed almost the same schools that had participated previously in Phase One. After questionnaires were collected we had to send them to Cartagena (our country coordinating centre) so they could be scanned in order to undergo a new processing system that made data analysis faster and easier. Data from this study has allowed us to acknowledge changes in prevalence of asthma and allergies in our paediatric population in Madrid.