Local Publications

The following publications used ISAAC data from the Munich centre:

  • Wellie O, Duhme H, Streit U, von Mutius E, Keil U, Weiland SK. Application of geographical information systems in epidemiological studies exemplified by the ISAAC study in Munich. Gesundheitswesen.2000 Aug-Sep;62(8-9):423-30.German.
  • Pinto LA, Steudemann L, Depner M, Klopp N, Illig T, Weiland SK, von Mutius E, Kabesch M. STAT1 gene variations, IgE regulation and atopy. Allergy 2007 Dec; 62(12):1456-61.
  • Schedel M, Pinto LA, Schaub B, Rosenstiel P, Cherkasov D, Cameron L, Klopp N, Illig T, Vogelberg C, Weiland SK, von Mutius E, Lohoff M, Kabesch M. IRF-1 gene variations influence IgE regulation and atopy. Am J Respir Crit Care Med.177(6):613-21, 2008 Mar 15.
  • Büchele G, Rzehak P, Weinmayr G, Keil U, Leupold W, von Mutius E, Weiland SK. Assessing bronchial responsiveness to hypertonic saline using the stepwise protocol of Phase II of the International Study of Asthma and Allergies in Childhood (ISAAC II). Pediatr Pulmonol 2007 Feb;42(2):131-40.
  • Bolte G, Kompauer I, Fobker M, Cullen P, Keil U, Mutius E, Weiland SK. Fatty acids in serum cholesteryl esters in relation to asthma and lung function in children. Clin Exp Allergy 2006 Mar;36(3):293-302.
  • von Ehrenstein OS, Maier EM, Weiland SK, Carr D, Hirsch T, Nicolai T, Roscher AA, von Mutius E. Alpha1 antitrypsin and the prevalence and severity of asthma. Arch Dis Child.2004 Mar;89(3):230-1.
  • Riu E, Dressel H, Windstetter D, Weinmayr G, Weiland S, Vogelberg C, Leupold W, von Mutius E, Nowak D, Radon K. First months of employment and new onset of rhinitis in adolescents. Eur Respir J.2007 Sep;30(3):549-55.Epub May 2007.
  • von Mutius E, Illi S, Hirsch T, Leupold W, Keil U, Weiland SK. Frequency of infections and risk of asthma, atopy and airway hyperresponsiveness in children. Eur Respir J.1999 Jul;14(1):4-11.
  • Beimfohr C, Maziak W, von Mutius E, Hense HW, Leupold W, Hirsch T, Keil U, Weiland SK. The use of anti-asthmatic drugs in children: results of a community-based survey in Germany. Pharmacoepidemiol Drug Saf.2001 Jun-Jul;10(4):315-21.
  • Cameron L, Depner M, Kormann M, Klopp N, Illig T, von Mutius E, Kabesch M. Genetic variation in CRTh2 influences development of allergic phenotypes. Allergy 2009; 64(10): 1478-1485.
  • Zeilinger S, Pinto LA, Nockher WA, Depner M, Klopp N, Illig T, von Mutius E, Renz H, Kabesch M. The effect of BDNF gene variants on asthma in German children. Allergy 2009 Dec; 64(12): 1790-1794
  • Pinto LA, Depner M, Klopp N, Illig T, Vogelberg C, von Mutius E, Kabesch M. MMP-9 gene variants increase the risk for non- atopic asthma in children. Respir Res Feb 2010; 11: 23
  • Kreißl S, Radon K, Dressel H, Genuneit J, Kellberger J, Nowak D, von Mutius E, Weiland SK, Weinmayr G, Windstetter D, and Vogelberg C Body mass index change and atopic diseases are not always associated in children and adolescents Ann Allergy Asthma Immunol 2014; 113(4):440-444.e1

Munich Centre

Phase OnePhase TwoPhase Three
Centre:Munich, Germany ( Western Europe )
Principal Investigator:Professor Erika von Mutius
Age Groups:9-11, Timeframe: September 1995 to December 1996.
Sampling Frame:A random sample of school classes in the 9-11-year age-group across Munich.


Professor Erika von Mutius

Professor Erika von Mutius

Dr. von Haunersches University Children's Hospital
Ludwig-Maximilians University
Lindwurmstrasse 4



  • ISAAC Steering Committee
  • Phase Two Principal Investigator for Munich