Local Publications

The following publications used ISAAC data from the Salzburg centre:

  • Eder W, Gamper A, Oberfeld G, Riedler J. Prevalence and severity of bronchial asthma, allergic rhinitis and atopic dermatitis in Salzburg school children.[German]. Wien Klin Wochenschr.1998; 110(19): 669-77.
  • Riedler J, Gamper A, Eder W, Oberfeld G. Prevalence of bronchial hyperresponsiveness to 4.5% saline and its relation to asthma and allergy symptoms in Austrian children. Eur Respir J 1998; 11: 355–360
  • Eder W, A Gamper, G Oberfeld, J Riedler. Clinical follow-up of an epidemiological study of asthma and allergies in children [Klinische Nachuntersuchung einer epidemiologischen Studie über Asthma und Allergien im Kindesalter.](article in German). Wien Klin Wochenschr 1998; 110(19):678-685.

Salzburg Centre

Phase OnePhase TwoPhase Three
Centre:Salzburg, Austria ( Western Europe )
Principal Investigator:Dr Josef Riedler
Age Groups:13-14, 6-7Timeframe:13-14yr:March 1995 to April 1995
6-7yr:February 1995 to February 1995
Sampling Frame:


Univ.Prof.Dr. Josef Riedler

Univ.Prof.Dr. Josef Riedler

Kardinal Schwarzenberg''sches Krankenhaus
Abteilung für Kinder- und Jugendheilkunde
Kardinal-Schwarzenberg-Straße 2-6
A-5620 Schwarzach im Pongau


  • Phase One Principal Investigator for Salzburg

Salzburg Centre

During his research fellowship at the RCH in Melbourne Josef Riedler was intensively involved in the standardisation of airway challenge tests for epidemiological surveys, particularly for ISAAC. Together with Colin Robertson and Sandra Anderson he worked out a field protocol and manual for the 4.5% hypertonic saline challenge test to be used in children and adolescents. This test was then chosen by the ISAAC steering committee for Phase2 investigations all over the world. After his return to Salzburg, Josef Riedler was appointed ISAAC-National coordinator for Austria and performed Phase 1 studies in children 6-7 yr and 13-14 yr.

The prevalence studies in ISAAC-Phase 1 in Salzburg were the first epidemiological studies on asthma and allergies in children in Austria and built a platform for further international collaborative investigations into risk and protective factors for the development of asthma and allergies in children. Until 2004 in Salzburg and since then in Schwarzach, Josef Riedler and his research team have been heavily involved in large studies in the farming population (ALEX-, PARSIFAL-, FORALLVENT-, PASTURE-, EFRAIM-Study).