How well do questionnaires perform compared with physical examination in detecting flexural eczema? Findings from the International Study of Asthma and Allergies in Childhood (ISAAC) Phase Two.
C. Flohr, G. Weinmayr, S.K. Weiland (deceased), E. Addo-Yobo, I. Annesi-Maesano, B. Björkstén, L. Bråbäck, G. Büchele, M. Chico, P. Cooper, M. Clausen, N. El Sharif, A. Martinez Gimeno, R.S. Mathur, E. von Mutius, MM. Morales Suarez-Varela, N. Pearce, V. Svabe, G.W.K. Wong, M. Yu, N.S. Zhong, H.C. Williams and the ISAAC Phase Two Study Group.
Background: Questionnaires are widely used in epidemiological studies to measure eczema symptom prevalence, but there are concerns regarding their accuracy if used as a diagnostic tool.
Objectives: To compare the performance of a validated eczema symptom questionnaire and a standardized skin examination protocol employed in the second phase of the International Study of Asthma and Allergies in Childhood (ISAAC).
Methods: A total of 30 358 schoolchildren aged 812 years from 18 coun
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